CARDIAC ARRHYTHMIA IN ANTI-MOG IGG SEROPOSITIVE PATIENT WITH PHENOTYPE OF NEUROMYELITIS OPTICA SPECTRUM DISORDER

Compartilhe

Segue abaixo resumo de um dos trabalhos elaborados pela equipe do CIEM apresentados no BCTRIMS 2015:



INTRODUCTION:

 

Recently antibodies to myelin oligodendrocyte glycoprotein (anti-MOG) were identified in the serum of a small group of patients who meet diagnosis for neuromyelitis optica spectrum disorders (NMOSD). The exact relationship of these patients with the more characteristic group of patients with anti-aquaporin 4 (anti-AQP4) autoimmunity remains to be clarified.

The dorsomedial hypothalamus (DMH) plays a key role in integrating cardiovascular responses to stress. There is also a positive relationship between midbrain activity and potentially proarrhythmic abnormalities in ventricular repolarization during psychological and physical stress.